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The risk or severity of adverse effects can be increased when Nimesulide is combined with Benazepril. The risk or severity of adverse effects can be increased when Leflunomide is combined with Niflumic Acid. Amitriptyline; Chlordiazepoxide: (Moderate) Because lithium has the potential to impair cognitive and motor skills, caution is advisable during concurrent use of other medications with centrally-acting effects including anxiolytics, sedatives, and hypnotics. One other study reported benefit in 3 of 6 patients with Unverricht-Lundborg disease and 2 of 3 with myoclonic epilepsy with ragged red fibers (MERRF). A paste made from the root powder applied topically can treat boils, ulcers, and other skin irritations and infections. Caution is called for when giving tricyclic antidepressants to patients with with severe hepatic disease and tumours of the adrenal medulla (e.

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